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English Premier League clubs experienced contrasting fortunes in Tuesday's UEFA Champions League action, with Manchester United recovering from two goals down to beat Roma 3-2 while Aston Villa suffered a 3-0 defeat against Barcelona.
Villa travelled to Spain hoping to maintain their perfect start to the competition, having won their opening three matches.
However, Unai Emery's side could not extend that run against Barcelona, who produced an impressive performance at the Spotify Nou Camp.
Lamine Yamal gave the hosts an early advantage before Raphinha scored twice in the second half to complete a convincing victory.
Villa had opportunities to get back into the contest, with Matty Cash, Victor Lindelof and Johan Manzambi all threatening, but their failure to convert those chances proved costly.
The defeat ended Villa's unbeaten record and saw them drop to third in the league phase standings with nine points, level with Barcelona but behind on goal difference.
Manchester United, meanwhile, delivered one of the evening's most dramatic performances at Old Trafford.
Michael Carrick's team looked destined for another disappointing result after Matias Soule and Donyell Malen put Roma 2-0 ahead in the first half.
However, Bruno Fernandes converted a penalty to reduce the deficit before Matheus Cunha scored twice to secure a 3-2 victory.
Cunha's winning goal arrived four minutes before the end of normal time, although the Brazilian was later sent off after receiving a second booking.
The victory moved United to 17th in the standings with six points from four matches, ending their nine-game wait for a win.
While Villa remain among the leading teams despite their setback, United will need further positive results to improve their position.