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Paris Saint-Germain strengthened their grip on the UEFA Champions League standings following Tuesday's matches, while Barcelona moved above Aston Villa into second place after defeating the Premier League side 3-0.
PSG remain the only team with a perfect record among the four-match sides, collecting 12 points from four victories.
Their impressive 6-0 win against Villarreal also increased their goal difference to +15, having scored 20 goals and conceded five.
Barcelona's victory took them to nine points, level with Aston Villa, but the Spanish giants moved into second place with a superior goal difference of +8 compared to Villa's +6.
Villa, who had won their opening three matches, suffered their first defeat of the campaign and dropped to third.
Sporting CP also strengthened their position in the top eight after beating Shakhtar Donetsk 1-0.
The Portuguese side moved to sixth with nine points, while Bayern Munich climbed to eighth following their 2-0 success against Atletico Madrid.
Bayern now have eight points.
Inter Milan moved to 14th after beating Feyenoord 3-0, while LASK climbed to 15th following their 4-0 demolition of Slovan Bratislava.
Manchester United also improved their position after defeating Roma 3-2. Michael Carrick's side moved to 17th with six points, level with Inter, LASK and Galatasaray.
At the opposite end, Villarreal dropped to 29th after suffering their third defeat, while Feyenoord remained 30th with three points.
Lille are 34th with one point, while Slovan Bratislava occupy bottom place without a point after four matches.
With more league-phase fixtures remaining, the battle for positions continues to take shape.