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Myles Lewis-Skelly comes in at left-back in place of Riccardo Calafiori, while Mikel Merino is preferred to Bruno Guimaraes in midfield. Up top, Viktor Gyokeres will hope to emulate his goalscoring performances in both games against the Toffees last term, with Kai Havertz dropping to the bench which also includes Piero Hincapie again after he recovered from his ankle injury.
David Moyes meanwhile has made three switches to his team, which fell to their first defeat of the campaign at home to Chelsea last weekend.
Having indicated there may be some injury issues ahead of their trip to N5, he is without Jarad Branthwaite after this heavy collision with Emiliano Martinez, with Jake O’Brien partnering James Tarkowski in defence.
Merlin Rohl has moved to right-back, with Brennan Johnson coming in at right wing, and former Gunner Ainsley Maitland-Niles benched. Jack Grealish also misses out on the other flank, with Tyrique George coming in.
Arsenal: Raya, White, Gabriel, Konsa, Lewis-Skelly, Rice, Merino, Odegaard, Madueke, Eze, Gyokeres.
Subs: Arrizabalaga, Timber, Hincapie, Calafiori, Mosquera, Zubimendi, Guimaraes, Dowman, Havertz.
Everton: Pickford, Rohl, Tarkowski, O’Brien, Mykolenko, Garner, Armstrong, Dewsbury-Hall, Johnson, George, Barry.
Subs: Travers, King, Maitand-Niles, Keane, Norgaard, Hackney, Alcaraz, Dibling, Graham.