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Inter Milan will aim to maintain their strong start to the Serie A season when they host struggling Fiorentina, while Napoli welcome Roma in another important league match this weekend.
Inter top the table after winning six of their opening seven league matches and drawing one.
They also secured a 1-0 victory over Ukrainian champions Shakhtar Donetsk in the UEFA Champions League on Wednesday, with Carlos Augusto scoring a late winner at San Siro despite Alessandro Bastoni’s red card.
The Italian champions had lost their first two matches in Europe against Real Madrid and Club Brugge but have continued to impress in the domestic league.
However, Inter will be without several players because of injuries, including Benjamin Pavard and Lautaro Martinez. John Stones and Curtis Jones are also listed as unavailable.
Inter are expected to rely on Marcus Thuram and Francesco Pio Esposito in attack as they seek another victory to strengthen their position at the top of the table.
Fiorentina , meanwhile, have struggled despite spending heavily on new players during the summer.
After battling to avoid relegation last season, the club have again made a poor start and find themselves in the bottom three.
Fiorentina lost their opening three matches before appointing Paolo Vanoli, who initially helped the team collect four points from his first two games.
However, they have since suffered consecutive defeats. Their recent losses include a 2-1 defeat to Genoa and a 3-1 home loss to Como.
Napoli will host Roma in another major Serie A encounter, with both teams looking to strengthen their positions in the league.
Napoli suffered a 1-0 defeat to Venezia last Saturday, their third loss in seven league matches this season.
They have won three and drawn one in the same period. The defeat increased the pressure on coach Massimiliano Allegri, but his side responded with an exciting 4-3 victory over Bodø/Glimt in the UEFA Champions League on Tuesday.
Napoli have lost five of their last nine matches in all competitions, raising concerns about their consistency.
However, they will take confidence from their recent home form, having won their last three matches at home.