Lamar Jackson's return to the Baltimore Ravens lasted all of one play on Sunday.

The Ravens' star quarterback took the field after the Buffalo Bills scored a touchdown on their opening drive.

Jackson dropped back to pass and the throw was incomplete.

However, Bills' rusher Greg Rousseau hit Jackson's right hand and the quarterback immediately headed for the sidelines, leaving the field in obvious distress.

The training staff wrapped his hand in a towel and took him directly to the locker room, not even heading for the blue tent.

Evan Washburn of CBS reported it was a right thumb injury.

Tyler Huntley replaced Jackson, who had missed the previous three games with a high ankle sprain.