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Liverpool stars Bradley Barcola, Florian Wirtz and Alexander Isak come back into the starting XI as Andoni Iraola's side attempts to enter the Premier League title race by beating Arsenal at Anfield.
Alisson Becker is in goal, with Ronald Araujo, Jeremy Jacquet, Virgil van Dijk and Milos Kerkez lining up along the back four. Trey Nyoni is preferred over Ryan Gravenberch and partners Alexis Mac Allister, who has been in excellent form, in the center of midfield.
Barcola, Wirtz and Isak are joined by Cody Gakpo in attack, with the likes of Rio Ngumoha in reserve. Dominik Szoboszlai and Victor Munoz also return to the bench after injury.
"This is the last of our four successive home games," Iraola writes in his matchday program notes ahead of the huge clash.
"Given Arsenal arrive as league champions and joint-leaders, it would be fair to say that it is also the biggest test of that run. The team has done incredibly well so far.
"The three victories we have had in this period have all been hard-earned but in different ways they have also been well-deserved because as well as showing a range of qualities, we have also had to show a lot of character.
"It has also felt like the connection with Anfield is growing and this is something that gives me a lot of satisfaction. The truth is that the players play for you. This means representing you and it also means giving everything on your behalf.
"When this happens and the supporters respond, it gives everyone in the stadium a feeling that we are together and that we are all in together.
"I have still only been at Liverpool for a short time but I already know that when this happens this is a club that can create its own momentum.
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"This is what we are looking for. Momentum does not just happen, it has to be worked for in every single moment. Since losing to Manchester City, we have reacted in such a positive way and our aim now is for this to continue.
"This means we go into this fixture — and as I said at the outset it is a big one — with good feelings and we would very much like this to carry on.
"For this to happen, we are going to have to be very close to our best because we know the quality that Arsenal will bring and we are also aware that their ambitions today will not be any different to our own."