Osimhen opened the scoring for the hosts with a superb shot from inside the box one minute before the half hour mark following a pass from Barış Alper Yılmaz.

The Nigeria international doubled Galatasaray's lead from a header off Davinson Sánchez's shot one minute before the break.

The 27-year-old has now registered six goals and three assists in six league appearances for the Yellow and Reds this season.

İrfan Kahveci reduced the deficit for Fenerbahçe two minutes after the hour mark.

Galatasaray reclaimed top spot on the league table following the victory.