Thomas Tuchel has left Cole Palmer out of the England squad, along with Phil Foden and Kobbie Mainoo, but Jude Bellingham’s brother Jobe and Fulham midfielder Josh King have earned their first senior call-ups.

Chelsea’s Palmer was hugely disappointed when he was overlooked for the World Cup in the summer after a stop-start season due to injury, and he withdrew from the last England camp in September and October because of a minor fitness issue, but he has been back to his best this season with five goals and three assists in 11 appearances.

England made medical checks with Chelsea on Thursday over Palmer and according to Sky Sports News, those checks confirmed he was fully fit and ready to take a full part in England’s upcoming Nations League matches against Croatia and Spain.

Speaking about Palmer’s omission on Friday, Tuchel said the “door is always open” for him and added: “I guess everyone is desperate to play for England, Cole is no exception. It counts when you’re in camp. I said last time, he misses too many opportunities to impress. The players who were in camp built something extraordinary.

“It’s not personal. We’ll never assume Cole isn’t in the mindset to come and play for his country but the competition is on and the players in the [last] camp did an amazing job.”

Manchester United midfielder Mainoo also withdrew from the previous squad with an unspecified injury having failed to feature at the World Cup despite being selected.

Manchester City forward Foden remains out of favour despite contributing six goal involvements in as many games, having been overlooked for last summer’s tournament and the autumn squad.

However, the notable absences have created opportunities for first-time call-ups for King and Borussia Dortmund’s Jobe Bellingham, both of whom have previously represented England at youth level.

Defenders Trevoh Chalobah and Tino Livramento have both withdrawn through injury, while left-back Nico O’Reilly misses out after being deemed “not 100 per cent” by Manchester City head coach Enzo Maresca, but Real Madrid right-back Trent Alexander-Arnold retains his place in the squad.

Inter Milan full-back Djed Spence returns for the first time since the World Cup after an injury, while Arsenal defender Ben White is recalled after being overlooked since March, when some England supporters booed him.

Bournemouth midfielder Alex Scott is ruled out with a thigh injury, so Everton’s James Garner, who was called up as a replacement in the autumn, comes in.

Nottingham Forest forward Morgan Gibbs-White and Liverpool youngster Rio Ngumoha will look to fill the void left by injured England stalwarts Marcus Rashford and Bukayo Saka, with Arsenal winger Noni Madueke overlooked.