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Harry Kane is poised to make England history on Thursday when the Three Lions face Croatia in the Nations League at Wembley.
The Bayern Munich striker is set to become his country's most capped player, while there are several other intriguing storylines ahead of the game.
Here are five talking points ahead of the Wembley encounter.
Barring any last-minute problems, Kane will make his 126th England appearance, moving clear of former goalkeeper Peter Shilton to become the country's outright record appearance holder.
The milestone will come on home soil, with a sold-out Wembley crowd also getting the chance to celebrate the 33-year-old's recent Ballon d'Or triumph.
Kane has already scored 91 goals for England and has a habit of marking big occasions by finding the net. Few would bet against him moving another step closer to the century mark on his record-breaking night.
Ben White is back in the England squad for the first time since March, when he was booed by supporters on his return following his controversial departure from the 2022 World Cup.
England boss Thomas Tuchel has urged fans to put the episode behind them, while the Arsenal defender suggested this week that supporters might think differently if they knew the full story of what happened in Qatar.
White could get another opportunity to impress at right-back, where he appears to be competing with Trent Alexander-Arnold for a starting place.
Tuchel has some important decisions to make at the back, with his preferred centre-half partnership of Marc Guehi and Ezri Konsa both ruled out of the Croatia clash through injury.
Newcastle defender Dan Burn has been recalled for the first time since the summer's World Cup, while Bournemouth's James Hill has earned his first senior call-up.
Jarrad Branthwaite is another option, although Jarell Quansah could be handed another start after featuring at centre-back in England's previous match.
Jude and Jobe Bellingham could make a little history of their own by becoming the first brothers to play together for England since Gary and Phil Neville in 2007.
Jude is already an established figure in the national team, while younger brother Jobe has received his first senior call-up following impressive displays for England Under-21s and Borussia Dortmund.
Jobe is unlikely to displace Declan Rice or Elliot Anderson in the starting line-up, but an appearance from the bench could see the brothers share the pitch for the first time in England colours.
It would also make them the 22nd set of brothers to represent the senior national team.
England are already within touching distance of the Nations League semi-finals but can make their qualification certain against Croatia.
A win or draw at Wembley would guarantee at least second place in the group, while victory would set up a showdown with Spain on Sunday for top spot.
Even defeat would not necessarily spell disaster, with England holding a significant goal difference advantage over Croatia following their emphatic 7-0 victory in Rijeka last month.